An accepted manuscript published in ARRS’ American Journal of Roentgenology (AJR) guides optimization of clinical protocols when implementing ultra-high-resolution photon-counting detector (UHR PCD) CT of the lungs, providing insights on the association of reconstruction kernel and slice thickness with image quality.

Evaluating the impact of kernel and slice thickness on image quality of UHR PCD CT of the lungs using a 1024×1024 matrix, “the sharpest evaluated kernel, BI64, was the optimal kernel, consistent with the current clinical-reference technique,” wrote corresponding author Helmut Prosch from the department of biomedical imaging and image-guided therapy at the Medical University of Vienna in Austria.

In this AJR accepted manuscript, 29 patients (17 women, 12 men; median age, 56 years) underwent non-contrast chest CT using a first-generation PCD scanner (Siemens Healthineers’ NAEOTOM Alpha) from February 15 to March 15, 2022. All acquisitions used UHR mode. Nine image sets were reconstructed for all combinations of three sharp kernels (BI56, BI60, BI64) and three slice thicknesses (0.2, 0.4, 1.0 mm). Three radiologists independently reviewed reconstructions for measures of visualization of pulmonary anatomic structures and pathologies using clinical-reference: BI641.0-mm.

Ultimately, when performing PCD CT of the lungs in UHR mode, reconstruction using BI64 kernel and 0.4-mm slice thickness was the only assessed reconstruction to yield improved bronchial division identification and bronchial wall and pulmonary fissure sharpness, without loss in pulmonary vessel sharpness or conspicuity of nodules or other pathologies.

In comparison, a 0.2-mm slice thickness—the thinnest reconstruction possible—was “associated with decreased visualization of various anatomic and pathologic findings,” the authors of this AJR accepted manuscript add